ANDREW J. PIERCE, Ph.D.
Publication Reprints
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2014 Michael W. Killen, Dawn M. Stults and Andrew J. Pierce.
The gene cluster instability (GCI) assay for recombination.
Methods in Molecular Biology 1105: 457-79
PubMed
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2014 Dawn M. Stults, Michael W. Killen and Andrew J. Pierce.
The sister chromatid exchange (SCE) assay.
Methods in Molecular Biology 1105: 439-55
PubMed
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2014 Andrew J. Pierce and Maria Jasin.
Measuring recombination proficiency in mouse embryonic stem cells.
Methods in Molecular Biology 1105: 481-95 updated reprint of 2004 paper
PubMed
PDF
2012 Michael W. Killen, Dawn M. Stults, William A. Wilson and Andrew J. Pierce.
Escherichia coli RecG functionally suppresses human Bloom syndrome phenotypes.
BMC Molecular Biology 13:33
PubMed
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2011 Michael W. Killen, Tiffany L. Taylor, Dawn M. Stults, Weidong Jin, Lisa L. Wang, Jeffrey A. Moscow and Andrew J. Pierce.
Configuration and rearrangement of the human GAGE gene clusters.
American Journal of Translational Research 3: 234-42.
PubMed
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2011 Dawn M. Stults, Michael W. Killen, Brent J. Shelton and Andrew J. Pierce.
Recombination phenotypes of the NCI-60 collection of human cancer cells.
BMC Molecular Biology 12:23
PubMed
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2011 Changanamkandath Rajesh, Dustin Baker, Andrew J. Pierce and Douglas L. Pittman.
The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion.
Nucleic Acids Research 39: 132-45.
PubMed
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2010 David Zaitlin and Andrew J. Pierce.
Nuclear DNA content in Sinningia Nees (Gesneriaceae); intraspecific genome size variation and genome characterization in S. speciosa.
Genome 53: 1066-82.
PubMed
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2010 Thiyam Ramsing Singh, Dorina Saro, Abdullah Mahmood Ali, Xiao-feng Zheng, Chang-hu Du, Michael W. Killen, Aristidis Sachpatzidis, Kebola Wahengbam, Andrew J. Pierce, Yong Xiong, Patrick Sung and Amom Ruhikanta Meetei.
MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM.
Molecular Cell 37: 879-86.
PubMed
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2009 Dawn M. Stults, Michael W. Killen, Erica P. Williamson, Jon S. Hourigan, H. David Vargas, Susanne M. Arnold, Jeffrey A. Moscow and Andrew J. Pierce.
Human ribosomal RNA gene clusters are recombinational hotspots in cancer.
Cancer Research 69: 9096-104.
More than half of adult solid tumors undergo recombination-mediated genomic alteration.
PubMed
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2009 Michael W. Killen, Dawn M. Stults, Noritaka Adachi, Les Hanakahi and Andrew J. Pierce.
Loss of Bloom syndrome protein destabilizes human gene cluster architecture.
Human Molecular Genetics 18(18): 3417-3428.
PubMed
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2009 Jasmina Kurepa, Songhu Wang, Yan Li, David Zaitlin, Andrew J. Pierce and Jan A. Smalle.
Loss of 26S proteasome function leads to increased cell size and decreased cell number in Arabidopsis shoot organs.
Plant Physiology
150(1): 178-189.
PubMed
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2008 Dawn M. Stults, Michael W. Killen, Heather H. Pierce, Andrew J. Pierce.
Genomic architecture and inheritance of human ribosomal RNA gene clusters.
Genome Research 18(1): 13-18.
The genomic structure of genes responsible for all protein synthesis changes with every human generation.
PubMed
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2005 Ranjit S. Bindra, Shannon L. Gibson, Alice Meng, Ulrica Westermark, Maria Jasin, Andrew J. Pierce, Robert G. Bristow, Marie K. Classon and Peter M. Glazer.
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.
Cancer Research
65(24): 11597-11604.
PubMed
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2005
Koji Nakanishi, Yun-Gui Yang, Andrew J. Pierce, Toshiyasu Taniguchi, Martin Digweed, Alan D. D’Andrea, Zhao-Qi Wang and Maria Jasin.
Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair.
Proceedings of the National Academy of Science
102(4): 1110-1115.
PubMed
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2004

Andrew J. Pierce and Maria Jasin.
Measuring recombination proficiency in mouse embryonic stem cells.
Methods in Molecular Biology 291:373-384.

PubMed
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2004

Jeremy M. Stark, Andrew J. Pierce, Jin Oh, Albert Pastink and Maria Jasin.
Genetic steps of mammalian homologous repair with distinct mutagenic consequences.
Molecular and Cellular Biology 24(21): 9305-9316.

PubMed
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2002

Felipe D. Araujo, Andrew J. Pierce, Jeremy M. Stark and Maria Jasin.
Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks.
Oncogene 21(26): 4176-4180.

PubMed
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2002

Jeremy M. Stark, Peng Hu, Andrew J. Pierce, Mary Ellen Moynahan, Nathan Ellis, and Maria Jasin.
ATP-hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair.
Journal of Biological Chemistry 277(23): 20185-20194.

PubMed
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2002

Claudia Wiese, Andrew J. Pierce, Stacey S. Gauny, Maria Jasin and Amy Kronenberg.
Gene conversion is strongly induced in human cells by double-strand breaks and is modulated by the expression of BCL-xL.
Cancer Research 62(5): 1279-1283.

PubMed
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2001

Andrew J. Pierce and Maria Jasin.
NHEJ deficiency and disease.
Molecular Cell 8(6): 1160-1161.

PubMed
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2001

Andrew J. Pierce, Peng Hu, Mingguang Han, Nathan Ellis and Maria Jasin.
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells.
Genes and Development 15(24): 3237-3242.

PubMed
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2001

Artur Slupianek, Christoph Schmutte, Gregory Tombline, Malgorzata Nieborowska-Skorska, Grazyna Hoser, Michal O. Nowicki, Andrew J. Pierce, Richard Fishel and Tomasz Skorski.
BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance.
Molecular Cell 8(4): 795-806.

PubMed
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2001

Andrew J. Pierce, Jeremy M. Stark, Felipe D. Araujo, Mary Ellen Moynahan, Marianne Berwick and Maria Jasin.
Double-strand breaks and tumorigenesis.
Trends in Cell Biology 11(11): S52-59.

PubMed
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2001

Mary Ellen Moynahan, Andrew J. Pierce and Maria Jasin.
BRCA2 is required for homology-directed repair of chromosomal breaks.
Molecular Cell 7(2): 263-272.

PubMed
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1999

Andrew J. Pierce, Roger D. Johnson and Maria Jasin.
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells.
Genes and Development 13(20): 2633-2638.
Describes an assay for recombination now standard in the field.  Cited hundreds of times.

PubMed
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1997

Matthew J. Longley, Andrew J. Pierce and Paul Modrich.
DNA Polymerase δ is Required for Human Mismatch Repair in Vitro.
Journal of Biological Chemistry 272(16): 10917-10921.

PubMed
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1993

Jane C. Azizkhan, David E. Jensen, Andrew J. Pierce, and Michael Wade.
Transcription from TATA-less Promoters: Dihydrofolate Reductase as a Model.
Critical Reviews in Eukaryotic Gene Expression 3(4): 229-254.

PubMed

1992

Andrew J. Pierce, Robert C. Jambou, David E. Jensen and Jane Clifford Azizkhan.
A Conserved DNA Structural Control Element Modulates Transcription of a Mammalian Gene.
Nucleic Acids Research 20(24): 6583-6587.

PubMed
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